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Making the Diagnosis of Down Syndrome

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Updated October 12, 2009

Written or reviewed by a board-certified physician. See About.com's Medical Review Board.

Another physical features seen in infants with Down syndrome is a single crease across the palms of their hands. This doesn't cause them any problems - their hands will work fine - but it is a sign that your pediatrician will be looking for if he suspects that your baby has Down syndrome. Other hand differences sometimes seen in infants with Down syndrome include short stubby fingers and a fifth finger or pinky that curves inward, a condition called clinodactyly.

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