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Making the Diagnosis of Down Syndrome

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Updated October 12, 2009

Written or reviewed by a board-certified physician. See About.com's Medical Review Board.

About 10% of infants with Down syndrome will have gastrointestinal issues such as a narrowing or blockage of the intestines (duodenal atresia), an absent anal opening (anal atresia), an obstruction of the outlet of the stomach (pyloric stenosis), or an absence of the nerves in the colon, called Hirschsprung’s disease. Most of these malformations can be fixed with surgery.

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